Crohn’s disease patients effectively mobilize peripheral blood stem cells to perform autologous haematopoietic stem cell transplantation
Crohn’s disease is an extremely debilitating condition of the intestinal tract that affects as many as 1.6 million Americans, most of whom are diagnosed before the age of 35. About 907,000 of those suffer from what is called ulcerative colitis. The disease can radically change one’s lifestyle, turning any errand away from home into a stress-filled adventure that can often turn into an embarrassing fiasco.
For most, it is often a very painful and gut wrenching illness that can flare up at any time, but usually triggered by certain foods that turn eating into something unpleasant. During these flares (think solar eruptions!), life can be downright miserable for the person stricken with this disease.
Recently stem cell therapy has been gaining favor and the interest of more practitioners and researchers in light of several new reports that are showing promise – purporting stems cell treatment to be even better than pharmaceutical drugs that can cost over $10,000 a month.
But even more encouraging, are the reports and findings that certain stem cell resources in the body can actually treat the underlying cause of Crohn’s disease.
One such element in this new procedure is Stromal Vascular Fraction, which is recovered by processing fat tissue after a mini-liposuction procedure is undertaken, which is very non-invasive and takes only about 30min. After this procedure, the fat is off to process in the lab.
An an hour later those same cells are then made ready to be administered through iv for about 45min. The stromal vascular fraction (SVF) has been found to have remarkable attributes. In particular, the stem cells and extracellular vesicles are able to down-regulate immune cells through a series of cell-to-cell communications.
The adipose (fat) tissue stem cells seem to be especially gifted in their ability to modulate the immune system in a beneficial way. And this ability is not confined benefitting Crohn’s exclusively, but a whole host of immune system dysfunctions are addressed and treated as well during the same procedure.
This is extremely encouraging news for those who suffer with immune system problems – for example cancer patients whose immune system has been greatly compromised of nearly destroyed from the treatments.
In short, it certainly looks like a cure is on the way and close to being revealed in short order. I am convinced that in the near future this use of stem cells as a treatment for Crohn’s disease will be a very common procedure and will also be used for curing autoimmune diseases.
Original blog piece was written by Dr. Bean of MyStemCell.com and reproduced with permission.